Senior Research Associate – Biosystems

Full time

Framingham, MA

A Research Associate position is available immediately with the R&D team. The Senior Research Associate will report to a Principal Scientist in Oncology R&D and will work with scientific staff focused on oncology drug discovery and development.


  • Perform the full spectrum of laboratory activities and independently develop, troubleshoot, and optimize cell-based assays in support of drug discovery and development efforts
  • Assess potency and target engagement of novel compounds using multiple techniques (e.g., Western, flow cytometry, plate-based endpoints, MSD)
  • Maintain laboratory records and notebook, organize and compile data, and write and present comprehensive reports on results
  • Facilitate interactions with external partners/CROs relevant to experimental projects
  • Handle laboratory workflows, coordinate activities of other personnel, and participate in project/timeline management
  • Assist junior team members
  • Other duties as assigned


  • Requires a BS in biology, biochemistry, or a related field and 3-5 years of laboratory experience is required or a MS in biology, biochemistry, or a related field plus 2 years of laboratory experience. Experience in the pharmaceutical industry setting is preferred.
  • Demonstrated proficiency in the assessment of target engagement, identification, and validation of early efficacy biomarkers, and in vitro pharmacology.
  • Laboratory skills in mammalian cell culture, common molecular techniques and; experience in cell-based assay development is required.
  • A highly motivated individual with excellent communication and interpersonal skills.
  • Must be able to work in a collaborative, team-oriented environment and demonstrate attention to detail and record-keeping.
  • Knowledge of Microsoft Word, GraphPad Prism, and PowerPoint is needed for the preparation of reports to management

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